How do I calculate peptide concentration after adding water?

Divide the amount in the vial by the volume of water you added. A 10 mg vial mixed with 2 mL gives 10 ÷ 2 = 5 mg/mL, which is the same as 5,000 mcg/mL.

How many units are in 1 mL on a U-100 syringe?

A U-100 insulin syringe is marked so that 100 units equal 1 mL. Each unit is 0.01 mL, so 0.25 mL reads as 25 units.

How do I convert mg to mcg?

Multiply milligrams by 1,000. 1 mg = 1,000 mcg, so 0.25 mg = 250 mcg. To go back, divide mcg by 1,000.

Can I convert units on the syringe back to an amount?

Yes. Divide the units by 100 to get mL, then multiply by the concentration. 20 units = 0.20 mL; at 5 mg/mL that holds 1 mg. The calculator does this when you type units into the units box.

Does adding more water change how much is in the vial?

No. The total in the vial stays the same. More water lowers the concentration, so the same amount takes up more volume and more units on the syringe.

Why is IU treated differently from mg?

IU measures biological activity, not weight, so there is no universal IU-to-mg rule. The calculator uses the IU count printed on your own vial label instead of guessing.

Does PeptideWhiz suggest doses?

No. PeptideWhiz never suggests or recommends an amount. Every number comes from you, and the tool only does the arithmetic. It is not medical advice.

Do I need an account to use the calculator?

No. The calculator is free and works without an account. An account only lets you save results to your stack and tracker.

Peptide Calculator

Vial and water math for Tesamorelin, with a research record of published human trials. Math only, no suggested amounts.

Free · no account needed

Compound (Optional)

Desired Amount Per Dose

units (U-100)

Vial Strength (Total mg of Your Vial)

Reconstitution Solution Added

Titration Schedule (Optional)

Results

Draw to

—units

Enter amount, vial and Reconstitution Solution

ConcentrationConc.

—mg/mL

Your dose

—mg

Doses / vial

—

More than 100 units (over 1 mL). This won't fit in a single U-100 syringe draw. Double-check your numbers or use more water / a smaller amount.

U-100 Syringe · 1 mL

Notes

PeptideWhizpeptidewhiz.app · research use only

Research use only (RUO). Results are math on the values you enter only, not a recommendation or prescription for human use. Not medical advice. Always verify your own measurements. Full disclaimer

About Tesamorelin

Tesamorelin is a stabilised analogue of human GHRH, the hypothalamic hormone that signals the pituitary to release growth hormone. A small chemical group added to the start of the chain protects it from rapid breakdown.

Research status

Tesamorelin is FDA-approved as a prescription medicine (Egrifta) to reduce excess abdominal fat in people with HIV-associated lipodystrophy. Research has since extended to liver fat and cognition in published trials.

How the math works for any vial (concentration, U-100 units, mg and mcg) is explained step by step on the main peptide reconstitution calculator page. Read the full What is Tesamorelin? guide for mechanism, trials and conditions researched.

What published studies used

Research record, not a recommendation or protocol

These are published human trials of Tesamorelin from the PeptideWhiz study library. The last column quotes each study’s PubMed abstract word for word, so it shows what that study reported giving its participants under medical supervision. It is not advice, and the calculator never fills these numbers in on its own: you can copy one only by tapping its button and confirming.

Study	Year	Journal	As reported in the abstract	PubMed
Efficacy and safety of tesamorelin in people with HIV on integrase inhibitors.	2024	AIDS (London, England)	“We leveraged a randomized double-blind trial of 61 PWH and metabolic dysfunction-associated steatotic liver disease to evaluate the efficacy and safety of tesamorelin 2 mg once daily vs. identical placebo among participants on INSTI-based regimens at baseline.”	PMID 38905488
Effects of tesamorelin on non-alcoholic fatty liver disease in HIV: a randomised, double-blind, multicentre trial.	2019	The lancet. HIV	“Participants were randomly assigned (1:1) to receive either tesamorelin 2 mg once daily or placebo once daily for 12 months, followed by a 6-month open-label phase during which all participants received tesamorelin 2 mg daily.”	PMID 31611038
Effect of tesamorelin on visceral fat and liver fat in HIV-infected patients with abdominal fat accumulation: a randomized clinical trial.	2014	JAMA	“Participants were randomized to receive tesamorelin, 2 mg (n=28), or placebo (n=22), subcutaneously daily for 6 months.”	PMID 25038357
Growth hormone-releasing hormone effects on brain γ-aminobutyric acid levels in mild cognitive impairment and healthy aging.	2013	JAMA neurology	“Participants self-administered daily subcutaneous injections of tesamorelin (Theratechnologies Inc), a stabilized analogue of human GHRH (1 mg/d), or placebo 30 minutes before bedtime for 20 weeks.”	PMID 23689947
Effects of tesamorelin, a growth hormone-releasing factor, in HIV-infected patients with abdominal fat accumulation: a randomized placebo-controlled trial with a safety extension.	2010	Journal of acquired immune deficiency syndromes (1999)	“In the primary efficacy phase (months 0-6), patients were randomly assigned to receive tesamorelin [2 mg subcutaneous (SC) every day] or placebo in a 2:1 ratio.”	PMID 20101189

Disclaimer: this table is an educational research record. It does not recommend, suggest or endorse any amount, schedule or use, and it is not medical advice. Decisions about any medicine belong with a licensed clinician.

Tesamorelin calculator FAQ

What is Tesamorelin?

Tesamorelin is a growth hormone-releasing hormone (GHRH) analogue. Tesamorelin is a stabilised analogue of human GHRH, the hypothalamic hormone that signals the pituitary to release growth hormone.

Is Tesamorelin approved?

Does this page suggest a Tesamorelin dose?

No. The calculator dose field starts empty and PeptideWhiz never suggests, recommends or calculates an amount for anyone. The study table is a research record of what published trials reported, not a recommendation or protocol.

Where do the study numbers on this page come from?

Each row quotes the abstract of a published human trial (5 trials, 2010 to 2024) word for word, as indexed in PubMed, with a link to the PubMed record. Nothing is rounded, combined or converted.

How does the calculator work with a Tesamorelin vial?

Pick Tesamorelin in step 1 if you want it on your result card, then enter the vial amount printed on your own label and the water volume actually added. The tool divides one by the other for concentration and shows the matching U-100 syringe units for an amount you type. Pens and pre-filled syringes are already in liquid form and are not reconstituted.

Sources

Study rows: PubMed records linked in the table (abstracts checked against PubMed on October 31, 2026). Unit math: see the sources on the main calculator.

Reviewed by the PeptideWhiz team on October 31, 2026. For research and education only.