Oxytocin Effects on Likeability After Being Liked or Disliked

What Was Tested

In this not phased trial, researchers set out to test Oxytocin.

The current study aimed to investigate oxytocin effect on the response after the experience of being liked or disliked.

It had two arms (groups): Oxytocin nasal spray (experimental) and Placebo nasal spray (placebo comparator).

Oxytocin nasal spray.

Placebo nasal spray.

The registry classes the interventions as drug.

More on the Plan

After that, they rated 'other participants' about likeability (how much do you like the person), accuracy (have you seen the person), feeling (how good do you feel), and tendency (how much would do like have him/her as a friend).

Likeability, tendency, feeling and accuracy were included into analysis as dependent variables.

Who Took Part

The registry lists 86 actual participants took part.

It was open to men only aged from 18 years up to 30 years.

Healthy volunteers could join, not only people with the condition.

Examples of who could join: Healthy subjects without past or current psychiatric or neurological disorder.

The full record lists 1 inclusion and 3 exclusion criteria; among the exclusions: history of head injury;; medical or psychiatric illness.

How the Study Was Run

Design: randomized, parallel-group and double-blind.

The participants were allocated by chance, so the Oxytocin group and the comparison group should start out alike.

The Oxytocin group and the comparison group ran side by side rather than switching.

Blinding on both sides kept the participants and researchers unaware of who received Oxytocin.

Those kept unaware of assignments: participant and investigator.

It started in 2015-06 with completion listed for 2016-06.

It ran at 1 site in China.

Its stated primary purpose is basic science.

What Was Measured

Researchers chose this as the main measure: Oxytocin effect on likeability after being liked or disliked (time frame: 2 hour).

It also tracked 1 secondary outcome, for example Relationship status may influence oxytocin effect.

What This Means in Plain Language

Put simply, this is a not phased, randomized trial of Oxytocin in 86 people.

The trial is marked completed; no results are posted to the registry yet, so nothing here describes outcomes.

More context: the Oxytocin compound page, all human trials.