Role of Local Skin Incision Infiltration by Oxytocin On Wound Healing

What Was Tested

This registered not phased trial tested Oxytocin.

Wound complications are of the most common morbidities following cesarean section.

It had two arms (groups): Group A (experimental) and Group B (experimental).

The registry classes the interventions as drug.

More on the Plan

There is a wide range of topical and systemic treatments for the management of caesarean skin incision.

Topical treatments have side effects and hence are not considered as the treatment of choice for such incisions.

Oxytocin is a Nonapeptide hormone of a cyclic six amino-acid structure and a tail of three amino acids, responsible for initiation of the milk ejection reflex and stimulating the uterine contractions.

In this way, the principal hormone oxytocin and its fragments may take part in a behavioral sequence, ranging from approach and interaction to calm and relaxation.

Who Took Part

The registry lists 120 planned participants were the target.

It was open to women only aged from 20 years up to 35 years.

Healthy volunteers were not accepted; participants needed the condition being studied.

Examples of who could join: Age group from 20- 35 years old. Gestational age 37-41 weeks, and. Elective caesarean section due to obstetrics indication. The patient signed an Informed Consent Form authorizing their inclusion.

The full record lists 5 inclusion and 9 exclusion criteria; among the exclusions: multiparous women,; assisted vaginal delivery,; normal vaginal delivery,.

How the Study Was Run

It was run as a randomized, parallel-group and single-blind study.

Random assignment meant chance, not the researchers, decided who got Oxytocin and who got the comparison, which limits bias.

The Oxytocin group and the comparison group ran side by side rather than switching.

Only one side, usually the participants, was kept unaware of whether Oxytocin was given.

Those kept unaware of assignments: participant.

It started in 2023-03-01 with completion listed for 2025-03-01.

It ran at 1 site in Egypt.

Its stated primary purpose is treatment.

What Was Measured

The main thing measured (primary outcome): Wound healing after Oxytocin injecton (time frame: from baseline to 6 days after the Cesarean operation). Pain Relief (time frame: From base line to 6 hours postoperatively).

What This Means in Plain Language

Put simply, this is a not phased, randomized trial of Oxytocin in 120 people.

Its status is unknown; no results are posted to the registry yet, so nothing here describes outcomes.

More context: the Oxytocin compound page, all human trials.