Ginko Biloba Versus Desmopressin in Treatment of Children With Monosymptomatic Nocturnal Enuresis

What Was Tested

In this not phased trial, researchers set out to test Desmopressin.

Treatment is dominated by two approaches, enuresis alarm and drugs.

Treatment with drugs has largely been focused on tricyclic antidepressants especially imipramine or, more recently, antidiuretic agents such as desmopressin .

It had three arms (groups): Omegapress 0.2 (active comparator), Ginkobiloba (active comparator) and Omegapress+ ginkgobiloba (active comparator).

Omegapress 0.2 was been taken by the pt.

Drug was taken by the pt.

Both drugs were taken.

The registry classes the interventions as drug.

Who Took Part

The registry lists 90 actual participants took part.

It was open to people of any sex aged from 12 years with no upper age limit.

Healthy volunteers could join, not only people with the condition.

Examples of who could join: All patients with monosymptomatic nocturnal enuresis.

The full record lists 1 inclusion and 1 exclusion criteria; among the exclusions: patients with day and night enuresis.

How the Study Was Run

Design: randomized, parallel-group and open-label.

Because people in this Desmopressin study were split into groups at random, differences between the groups are less likely to reflect who happened to join each one.

Groups ran in parallel: each of the participants stayed in one arm throughout.

Being open-label, the Desmopressin study did not mask who received what.

It started in 2024-01-01 with completion listed for 2024-07-01.

It ran at 1 site in Egypt.

Its stated primary purpose is treatment.

What Was Measured

The main thing measured (primary outcome): To asses the effect of different drugs on number of bed time wetting (time frame: 3 months).

What This Means in Plain Language

Put simply, this is a not phased, randomized trial of Desmopressin in 90 people.

The trial is marked completed; no results are posted to the registry yet, so nothing here describes outcomes.

More context: the Desmopressin compound page, all human trials.