Endometrial estrogen and progesterone receptor and pinopode expression in stimulated cycles of oocyte donors

Plain-language guide to PMID 10360907 (1999): controlled clinical trial study of hCG (human chorionic gonadotropin), endometriosis.

Key Facts

PMID: 10360907
Journal: Fertility and sterility
Year: 1999
Study type: Controlled Clinical Trial
Authors: Develioglu OH et al. (6 authors)
DOI: 10.1016/s0015-0282(99)00137-5

What This Study Did, in Plain Language

What Was Tested

Researchers studied hCG (human chorionic gonadotropin) in the context of endometriosis in this controlled clinical trial publication.

To study the effect of controlled ovarian hyperstimulation and the ovarian response on several features of endometrial morphology simultaneously.

Who Took Part

PubMed tags the participants as women only.

Endometrial biopsies during the luteal phase and measurement of serum E2 and progesterone levels on days 12, 13, and 18-20.

How the Study Was Run

Twenty-five oocyte donors undergoing COH and 10 ovulatory controls.

What Was Measured

Topics PubMed links to this paper include Biopsy, Cell Membrane, Chorionic Gonadotropin, Endometrium, Estradiol, Luteal Phase and Microscopy, Electron, Scanning.

What This Means in Plain Language

This is a controlled clinical trial of hCG (human chorionic gonadotropin) in people with endometriosis.

The abstract goes on to report its results in about 6 sentences; this page does not restate them, so read the paper for the findings and their limits.

The publication is from 1999 (Fertility and sterility), a journal based in United States.

More context: the hCG (human chorionic gonadotropin) compound page, Endometriosis research.

Our Notes on the Compound

hCG (human chorionic gonadotropin): An LH analog that drives Leydig-cell testosterone production.

Source: PubMed record. This explanation is written by PeptideWhiz from the public record. For research and education only. Not medical advice; no dosing information is given.