Chronic acalculous cholecystitis: reproduction of pain with cholecystokinin and relief of symptoms with cholecystectomy

What Was Tested

Researchers studied Cholecystokinin (CCK) in the context of chronic pain: fibromyalgia & crps in this clinical trial publication.

Over 500,000 patients undergo cholecystectomy annually in the United States for symptoms of upper abdominal discomfort and pain ascribed to gallbladder disease.

These patients often present as challenging diagnostic dilemmas and are often treated as if their symptoms are secondary to peptic ulcer disease or other gastrointestinal-related disorders.

Who Took Part

The abstract describes 500,000 patients taking part.

The age groups tagged for this paper are adults, middle-aged adults and older adults, both men and women.

What Was Measured

These patients often present as challenging diagnostic dilemmas and are often treated as if their symptoms are secondary to peptic ulcer disease or other gastrointestinal-related disorders.

In 1992, the researchers began to use the cholecystokinin (CCK) challenge test on patients with normal ultrasound examinations of the gallbladder but who had chronic symptoms resembling biliary colic.

PubMed files the paper under topics including Abdominal Pain, Biliary Tract Diseases, Cholecystectomy, Cholecystitis, Cholecystokinin, Chronic Disease and Colic.

What This Means in Plain Language

This is a clinical trial of Cholecystokinin (CCK) in 500,000 patients in people with chronic pain: fibromyalgia & crps.

With several hundred people or more, it is a fairly large study for this kind of research.

The publication is from 1999 (South Dakota journal of medicine), a journal based in United States.

More context: the Cholecystokinin (CCK) compound page, Chronic pain: fibromyalgia & CRPS research.