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[Effect of recombinant growth hormone on amino acids metabolism in blood and urine after major operation].
Plain-language guide to PMID 10453490 (1997): double-blind randomized controlled trial of Exogenous HGH, sermorelin & older GHRPs (why they're passed over) in 18 patients.
Key Facts
- PMID
- 10453490
- Journal
- Zhongguo yi xue ke xue yuan xue bao. Acta Academiae Medicinae Sinicae
- Year
- 1997
- Study type
- Randomized Controlled Trial
- Authors
- He G et al. (5 authors)
What This Study Did, in Plain Language
What Was Tested
The paper reports a study of Exogenous HGH, sermorelin & older GHRPs (why they're passed over), published as a randomized controlled trial.
To determine the effects of recombinant human growth hormone (GH) on postoperative amino acids metabolism, the researchers performed a placebo-controlled randomized double-blind trial in 18 patients after elective gastrectomy or colectomy.
Why It Was Studied
The same amount of calories and amino acids were administered.
All urine were analyzed for nitrogen balance and excretion of 3-methylhistidine.
Who Took Part
The study group was 18 patients.
How the Study Was Run
The design is described as randomized, double-blind and placebo-controlled.
Because people in this Exogenous HGH, sermorelin & older GHRPs (why they're passed over) study were split into groups at random, differences between the groups are less likely to reflect who happened to join each one.
As a double-blind Exogenous HGH, sermorelin & older GHRPs (why they're passed over) study, the assignments were hidden from both participants and investigators until the end.
Some patients received a placebo instead of Exogenous HGH, sermorelin & older GHRPs (why they're passed over), giving a reference point.
On the seventh postoperative day while the parenteral nutrients were being infused, amino acid exchange across the forearm was measured.
What Was Measured
The subject headings attached to it are Amino Acids, Branched-Chain, Amino Acids, Essential, Colectomy, Gastrectomy, Growth Hormone, Methylhistidines and Phenylalanine.
What This Means in Plain Language
The paper is a randomized, double-blind and placebo-controlled study of Exogenous HGH, sermorelin & older GHRPs (why they're passed over) in 18 patients.
With fewer than 40 people, it is a small study, so it is better read as an early signal for further research than as a settled answer.
The publication is from 1997 (Zhongguo yi xue ke xue yuan xue bao. Acta Academiae Medicinae Sinicae), a journal based in China.
More context: the Exogenous HGH, sermorelin & older GHRPs (why they're passed over) compound page, all human trials.
Our Notes on the Compound
Exogenous HGH, sermorelin & older GHRPs (why they're passed over): Constant levels suppress the body's own GHRH, raise somatostatin and dull pituitary response.
Related Pages
Source: PubMed record. This explanation is written by PeptideWhiz from the public record. For research and education only. Not medical advice; no dosing information is given.