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The effects of long-term growth hormone treatment on cardiac left ventricular dimensions and blood pressure in girls with Turner's syndrome. Dutch Working Group on Growth Hormone.

Plain-language guide to PMID 10518081 (1999): randomized controlled trial of Exogenous HGH, sermorelin & older GHRPs (why they're passed over) in 68 girls, low blood pressure and orthostatic hypotension.

Key Facts

PMID
10518081
Journal
The Journal of pediatrics
Year
1999
Study type
Randomized Controlled Trial
Authors
Sas TC et al. (6 authors)
DOI
10.1016/s0022-3476(99)70170-8

What This Study Did, in Plain Language

What Was Tested

The paper reports a study of Exogenous HGH, sermorelin & older GHRPs (why they're passed over) in the context of low blood pressure and orthostatic hypotension, published as a randomized controlled trial.

To assess the effects of long-term growth hormone (GH) treatment for short stature on left ventricular (LV) dimensions and systemic blood pressure (BP) in girls with Turner's syndrome without clinically relevant cardiac abnormalities.

Who Took Part

The study group was 68 girls.

PubMed indexes the participants as children, women only.

How the Study Was Run

The researchers set it up as a randomized study.

Random assignment meant chance, not the researchers, decided who got Exogenous HGH, sermorelin & older GHRPs (why they're passed over) and who got the comparison, which limits bias.

What Was Measured

PubMed files the paper under topics including Blood Pressure, Echocardiography, Heart Ventricles, Human Growth Hormone, Hypertrophy, Left Ventricular and Turner Syndrome.

What This Means in Plain Language

The paper is a randomized study of Exogenous HGH, sermorelin & older GHRPs (why they're passed over) in 68 girls in people with low blood pressure and orthostatic hypotension.

The abstract goes on to report its results in about 10 sentences; this page does not restate them, so read the paper for the findings and their limits.

The publication is from 1999 (The Journal of pediatrics), a journal based in United States.

More context: the Exogenous HGH, sermorelin & older GHRPs (why they're passed over) compound page, Low blood pressure and orthostatic hypotension research.

Our Notes on the Compound

Exogenous HGH, sermorelin & older GHRPs (why they're passed over): Constant levels suppress the body's own GHRH, raise somatostatin and dull pituitary response.

Related Pages

Source: PubMed record. This explanation is written by PeptideWhiz from the public record. For research and education only. Not medical advice; no dosing information is given.