Acute tubular necrosis in patients with diabetes mellitus.

What Was Tested

The paper reports a study of Diuretics, published as a randomized controlled trial.

The researchers compared the clinical outcomes of patients with (n = 71) and without (n = 185) diabetes mellitus enrolled into the placebo arm of a large, multicenter clinical trial of patients with acute tubular necrosis (ATN).

By day 21 after enrollment, neither mortality nor dialysis-free survival was different between the groups.

Who Took Part

PubMed indexes the participants as middle-aged adults and older adults.

How the Study Was Run

The researchers set it up as a randomized, placebo-controlled and multicenter study.

Because people in this Diuretics study were split into groups at random, differences between the groups are less likely to reflect who happened to join each one.

The comparison arm used a placebo, so changes seen with Diuretics could be set against what happens without it.

Running at several centres spread the Diuretics study over different clinics and patient groups.

What Was Measured

The researchers compared the clinical outcomes of patients with (n = 71) and without (n = 185) diabetes mellitus enrolled into the placebo arm of a large, multicenter clinical trial of patients with acute tubular necrosis (ATN).

The subject headings attached to it are Atrial Natriuretic Factor, Diabetes Complications, Diabetes Mellitus, Diuretics, Kidney Tubular Necrosis, Acute, Peptide Fragments and Prognosis.

What This Means in Plain Language

The paper is a randomized, placebo-controlled and multicenter study of Diuretics.

The publication is from 1999 (American journal of kidney diseases : the official journal of the National Kidney Foundation), a journal based in United States.

More context: all human trials.