Effect of time exposure to high altitude on zinc and copper concentrations in human plasma

What Was Tested

This controlled clinical trial paper looks at Copper (Supplement).

Research has focused mainly on the relationship of zinc and copper contents and physical stresses like running, cycling, etc.

It has also been reported that other forms of stresses change the concentration of these trace elements in humans.

Who Took Part

By PubMed's age tags, the people studied were adults, men only.

Volunteers were divided into two groups: with and without zinc and copper salt supplementation.

How the Study Was Run

Blood samples were collected at sea level and on induction to acute hypoxia on days 3 and 10.

Trace mineral contents and their related enzyme (alkaline phosphatase) and hormone (ceruloplasmin) levels were determined in plasma samples.

What Was Measured

However,there are no reports on the effects of high altitude induced hypoxic stress on the plasma levels of these metals.

Since hypoxia is one of the important stresses, the researchers considered it appropriate to observe the changes in the levels of zinc and copper concentrations and in certain related zinc and copper enzymes and hormones in the plasma of human volunteers on acute induction to high altitude.

The subject headings attached to it are Acute Disease, Adaptation, Physiological, Alkaline Phosphatase, Altitude Sickness, Ceruloplasmin, Copper and Nutritional Requirements.

What This Means in Plain Language

This is a controlled clinical trial of Copper (Supplement).

Its findings take up roughly 6 sentences of the abstract and are left out here on purpose; the source paper is the place to read them.

The publication is from 1999 (Aviation, space, and environmental medicine), a journal based in United States.

More context: the Copper (Supplement) compound page, all human trials.