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Magnesium sulfate as a vehicle for nebulized salbutamol in acute asthma.

Plain-language guide to PMID 10723972 (2000): double-blind randomized controlled trial of Magnesium Sulfate in 35 patients.

Key Facts

PMID
10723972
Journal
The American journal of medicine
Year
2000
Study type
Randomized Controlled Trial
Authors
Nannini LJ et al. (5 authors)
DOI
10.1016/s0002-9343(99)00463-5

What This Study Did, in Plain Language

What Was Tested

The paper reports a study of Magnesium Sulfate, published as a randomized controlled trial.

Their goal was to determine if isotonic magnesium sulfate could be used as a vehicle for nebulized salbutamol for patients with acute asthma.

Who Took Part

The abstract describes 35 patients taking part.

The age groups tagged for this paper are adults and middle-aged adults, both men and women.

The researchers enrolled 35 patients with acute asthma in a randomized, double-blind, controlled trial.

Peak flow was reassessed 10 and 20 minutes after treatment.

How the Study Was Run

In design terms this was a randomized and double-blind study.

The patients were allocated by chance, so the Magnesium Sulfate group and the comparison group should start out alike.

As a double-blind Magnesium Sulfate study, the assignments were hidden from both participants and investigators until the end.

What Was Measured

The subject headings attached to it are Acute Disease, Administration, Inhalation, Albuterol, Asthma, Bronchodilator Agents, Isotonic Solutions and Magnesium Sulfate.

What This Means in Plain Language

The paper is a randomized and double-blind study of Magnesium Sulfate in 35 patients.

With fewer than 40 people, it is a small study, so it is better read as an early signal for further research than as a settled answer.

The abstract goes on to report its results in about 5 sentences; this page does not restate them, so read the paper for the findings and their limits.

The publication is from 2000 (The American journal of medicine), a journal based in United States.

More context: all human trials.

Related Pages

Source: PubMed record. This explanation is written by PeptideWhiz from the public record. For research and education only. Not medical advice; no dosing information is given.