Addition of inulin to breakfast does not acutely affect serum ionized calcium and parathyroid hormone concentrations

What Was Tested

The paper reports a study of Parathyroid Hormone (PTH 1-84), published as a randomized controlled trial.

The aim of the present study was to investigate the effects of inulin on calcium metabolism.

The study consisted of two separate parts both of which had a randomized two-period cross-over design.

Who Took Part

The age groups tagged for this paper are adults, women only.

Fifteen young healthy women volunteered to participate in this study.

How the Study Was Run

The design is described as randomized and crossover.

Random assignment meant chance, not the researchers, decided who got Parathyroid Hormone (PTH 1-84) and who got the comparison, which limits bias.

In the crossover set-up each of the participants took both Parathyroid Hormone (PTH 1-84) and the comparison in turn, acting as their own control.

The whole day's diet was standardized.

Before breakfast, and 2, 4, 6 and 8 h after breakfast, a blood sample was taken, and intact parathyroid hormone (iPTH), ionized calcium (iCa) and total calcium were measured.

Urine was collected throughout the day, and the 8-, 12- and 24-hour calcium excretion was calculated.

What Was Measured

Topics PubMed links to this paper include Area Under Curve, Calcium, Dietary Supplements, Eating, Intestinal Absorption, Inulin and Parathyroid Hormone.

What This Means in Plain Language

The paper is a randomized and crossover study of Parathyroid Hormone (PTH 1-84).

The abstract goes on to report its results in about 3 sentences; this page does not restate them, so read the paper for the findings and their limits.

The publication is from 1999 (Annals of nutrition & metabolism), a journal based in Switzerland.

More context: the Parathyroid Hormone (PTH 1-84) compound page, all human trials.