The effects of an oral multivitamin combination with calcium, magnesium, and zinc on psychological well-being in healthy young male volunteers: a double-blind placebo-controlled trial.

What Was Tested

This randomized controlled trial looks at Magnesium and Calcium.

The present study tested the effects of a multivitamin and mineral supplement (Berocca) on psychological well-being.

Who Took Part

According to the abstract, 80 volunteers were involved.

By PubMed's age tags, the people studied were teenagers and adults, men only.

In a double-blind randomised-control trial, 80 healthy male volunteers were assigned to either Berocca or placebo.

At the end of the study, the acceptability of the treatment and participants' awareness of treatment condition were assessed, as was habitual dietary behaviour.

How the Study Was Run

The design is described as randomized, double-blind and placebo-controlled.

The volunteers were allocated by chance, so the Magnesium group and the comparison group should start out alike.

Blinding on both sides kept the volunteers and researchers unaware of who received Magnesium.

Some volunteers received a placebo instead of Magnesium, giving a reference point.

What Was Measured

The subject headings attached to it are Analysis of Variance, Anxiety, Calcium, Chi-Square Distribution, Drug Combinations, Magnesium and Stress, Psychological.

What This Means in Plain Language

The paper is a randomized, double-blind and placebo-controlled study of Magnesium and Calcium in 80 volunteers.

Results are reported in around 5 sentences of the abstract; we leave them to the paper itself rather than summarise them.

The publication is from 2000 (Psychopharmacology), a journal based in Germany.

More context: the related Vitamin D, K2, Magnesium and Zinc library page, all human trials.