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Recombinant growth hormone (GH) therapy in GH-deficient adults: a long-term controlled study on daily versus thrice weekly injections.

Plain-language guide to PMID 11061530 (2000): randomized controlled trial of Exogenous HGH, sermorelin & older GHRPs (why they're passed over) in 34 patients.

Key Facts

PMID
11061530
Journal
The Journal of clinical endocrinology and metabolism
Year
2000
Study type
Randomized Controlled Trial
Authors
Amato G et al. (12 authors)
DOI
10.1210/jcem.85.10.6881

What This Study Did, in Plain Language

What Was Tested

This randomized controlled trial looks at Exogenous HGH, sermorelin & older GHRPs (why they're passed over).

This modality of treatment is not complied with by the totality of GHD patients, who are supposed to receive life-long replacement.

Thirty-four healthy subjects served as controls.

Who Took Part

The study group was 34 patients.

By PubMed's age tags, the people studied were adults and middle-aged adults, both men and women.

How the Study Was Run

The design is described as randomized.

Random assignment meant chance, not the researchers, decided who got Exogenous HGH, sermorelin & older GHRPs (why they're passed over) and who got the comparison, which limits bias.

What Was Measured

Conversely, patients included in groups A and B had similar serum IGF-I levels, lipid profile, body composition, bone metabolism, and bone density.

Topics PubMed links to this paper include Aging, Body Composition, Bone Density, Bone and Bones, Glucose Tolerance Test, Growth Hormone and Human Growth Hormone.

What This Means in Plain Language

The paper is a randomized study of Exogenous HGH, sermorelin & older GHRPs (why they're passed over) in 34 patients.

With fewer than 40 people, it is a small study, so it is better read as an early signal for further research than as a settled answer.

The publication is from 2000 (The Journal of clinical endocrinology and metabolism), a journal based in United States.

More context: the Exogenous HGH, sermorelin & older GHRPs (why they're passed over) compound page, all human trials.

Our Notes on the Compound

Exogenous HGH, sermorelin & older GHRPs (why they're passed over): Constant levels suppress the body's own GHRH, raise somatostatin and dull pituitary response.

Related Pages

Source: PubMed record. This explanation is written by PeptideWhiz from the public record. For research and education only. Not medical advice; no dosing information is given.