Body composition, blood pressure, and lipid metabolism before and during long-term growth hormone (GH) treatment in children with short stature born small for gestational age either with or without GH deficiency.

What Was Tested

The paper reports a study of Exogenous HGH, sermorelin & older GHRPs (why they're passed over) in the context of low blood pressure and orthostatic hypotension, published as a randomized controlled trial.

To assess the effects of long-term continuous GH treatment on body composition, blood pressure (BP), and lipid metabolism in children with short stature born small for gestational age (SGA), body mass index (BMI), skinfold thickness measurements, systemic BP measurements, and levels of blood lipids were evaluated in 79 children with a baseline age of 3-11 yr with short stature (height SD-score, < -1.88) born SGA (birth length SD-score, < -1.88).

Why It Was Studied

Twenty-two of the 79 children were GH deficient (GHD).

Who Took Part

The study group was 79 children.

By PubMed's age tags, the people studied were young children and children, both men and women.

How the Study Was Run

The researchers set it up as a randomized, double-blind and multicenter study.

The children were allocated by chance, so the Exogenous HGH, sermorelin & older GHRPs (why they're passed over) group and the comparison group should start out alike.

Neither the children nor the staff measuring them knew who was on Exogenous HGH, sermorelin & older GHRPs (why they're passed over), so expectations could not easily colour the readings.

More than one site took part, so the children came from several places.

What Was Measured

PubMed files the paper under topics including Blood Pressure, Body Composition, Body Mass Index, Growth Disorders, Growth Hormone, Human Growth Hormone and Infant, Small for Gestational Age.

What This Means in Plain Language

The paper is a randomized, double-blind and multicenter study of Exogenous HGH, sermorelin & older GHRPs (why they're passed over) in 79 children in people with low blood pressure and orthostatic hypotension.

The publication is from 2000 (The Journal of clinical endocrinology and metabolism), a journal based in United States.

More context: the Exogenous HGH, sermorelin & older GHRPs (why they're passed over) compound page, Low blood pressure and orthostatic hypotension research.