Effects of transdermal nicotine on craving, withdrawal and premenstrual symptomatology in short-term smoking abstinence during different phases of the menstrual cycle

What Was Tested

The paper reports a study of Therapeutic nicotine (patch, non-peptide), published as a randomized controlled trial.

Few studies, however, have directly assessed hormonal influences on nicotine response.

This study focused on the effects of a transdermal nicotine patch in women during acute smoking abstinence when tested in different phases of their menstrual cycle.

Who Took Part

PubMed indexes the participants as adults, women only.

Thirty women were randomized to order of menstrual cycle phase (late luteal or follicular) and patch condition (active or placebo).

How the Study Was Run

In design terms this was a randomized and placebo-controlled study.

The participants were allocated by chance, so the Therapeutic nicotine (patch, non-peptide) group and the comparison group should start out alike.

Some participants received a placebo instead of Therapeutic nicotine (patch, non-peptide), giving a reference point.

What Was Measured

Few studies, however, have directly assessed hormonal influences on nicotine response.

This study focused on the effects of a transdermal nicotine patch in women during acute smoking abstinence when tested in different phases of their menstrual cycle.

PubMed files the paper under topics including Administration, Cutaneous, Menstrual Cycle, Nicotine, Premenstrual Syndrome, Smoking Cessation, Substance Withdrawal Syndrome and Weight Gain.

What This Means in Plain Language

The paper is a randomized and placebo-controlled study of Therapeutic nicotine (patch, non-peptide).

The publication is from 2000 (Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco), a journal based in England.

More context: the Therapeutic nicotine (patch, non-peptide) compound page, all human trials.