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An evidence-based programme for smoking cessation: effectiveness in routine general practice.
Plain-language guide to PMID 11127170 (2000): randomized controlled clinical trial of Nicotine.
Key Facts
- PMID
- 11127170
- Journal
- The British journal of general practice : the journal of the Royal College of General Practitioners
- Year
- 2000
- Study type
- Controlled Clinical Trial
- Authors
- Grandes G et al. (3 authors)
What This Study Did, in Plain Language
What Was Tested
Researchers studied Nicotine in this controlled clinical trial publication.
To evaluate the results of a comprehensive smoking cessation programme in routine primary care practice.
Why It Was Studied
Smoking cessation clinical practice guidelines are based on randomised clinical trials reporting outcomes in persons who participate in these studies.
Who Took Part
The age groups tagged for this paper are teenagers, adults, middle-aged adults and older adults, both men and women.
The percentages of subjects in the intervention (n = 1203, seven practices) and control (n = 565, three practices) groups who reported sustained abstinence between six and 12 months follow-up and were validated biochemically were compared.
How the Study Was Run
In design terms this was a randomized study.
Random assignment meant chance, not the researchers, decided who got Nicotine and who got the comparison, which limits bias.
The effect of the programme was adjusted to baseline differences in both groups by multiple logistic regression analyses.
What Was Measured
Smoking cessation clinical practice guidelines are based on randomised clinical trials reporting outcomes in persons who participate in these studies.
Topics PubMed links to this paper include Administration, Cutaneous, Algorithms, Evidence-Based Medicine, Family Practice, Multivariate Analysis, Nicotine and Program Evaluation.
What This Means in Plain Language
The paper is a randomized study of Nicotine.
The abstract goes on to report its results in about 2 sentences; this page does not restate them, so read the paper for the findings and their limits.
The publication is from 2000 (The British journal of general practice : the journal of the Royal College of General Practitioners), a journal based in England.
More context: the related Therapeutic nicotine (patch, non-peptide) library page, all human trials.
Related Library Page
Therapeutic nicotine (patch, non-peptide): Pure nicotine as a signaling tool, separated from smoking and vaping.
Related Pages
Source: PubMed record. This explanation is written by PeptideWhiz from the public record. For research and education only. Not medical advice; no dosing information is given.