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Physical exercise and normobaric hypoxia: independent modulators of peripheral cholecystokinin metabolism in man

Plain-language guide to PMID 11133899 (2001): double-blind randomized controlled trial study of Cholecystokinin (CCK).

Key Facts

PMID
11133899
Journal
Journal of applied physiology (Bethesda, Md. : 1985)
Year
2001
Study type
Randomized Controlled Trial
Authors
Bailey DM et al. (5 authors)
DOI
10.1152/jappl.2001.90.1.105

What This Study Did, in Plain Language

What Was Tested

Researchers studied Cholecystokinin (CCK) in this randomized controlled trial publication.

The purpose of the present investigation was to determine the independent effects of hypoxia and physical exercise on peripheral cholecystokinin (CCK) metabolism in humans.

Why It Was Studied

Thirty-two physically active men were randomly assigned in a double-blind manner to either a normoxic (N; n = 14) or hypoxic (H; n = 18) group.

During the acute study, subjects in the H group only participated in two tests, separated by 48 h, which involved a cycling test to exhaustion in normobaric normoxia and normobaric hypoxia (inspired O(2) fraction = 0.21 and 0.16, respectively).

Who Took Part

The age groups tagged for this paper are adults, men only.

How the Study Was Run

The researchers set it up as a randomized and double-blind study.

Because people in this Cholecystokinin (CCK) study were split into groups at random, differences between the groups are less likely to reflect who happened to join each one.

Blinding on both sides kept the participants and researchers unaware of who received Cholecystokinin (CCK).

What Was Measured

During the acute study, subjects in the H group only participated in two tests, separated by 48 h, which involved a cycling test to exhaustion in normobaric normoxia and normobaric hypoxia (inspired O(2) fraction = 0.21 and 0.16, respectively).

PubMed files the paper under topics including Amino Acids, Branched-Chain, Anthropometry, Atmospheric Pressure, Blood Glucose, Cholecystokinin, Diet and Energy Intake.

What This Means in Plain Language

The paper is a randomized and double-blind study of Cholecystokinin (CCK).

The publication is from 2001 (Journal of applied physiology (Bethesda, Md. : 1985)), a journal based in United States.

More context: the Cholecystokinin (CCK) compound page, all human trials.

Our Notes on the Compound

Cholecystokinin (CCK): A gut and brain peptide hormone that stimulates gallbladder contraction and signals fullness.

Related Pages

Source: PubMed record. This explanation is written by PeptideWhiz from the public record. For research and education only. Not medical advice; no dosing information is given.