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The effect of growth hormone on 24-h urinary creatinine levels in burned patients.

Plain-language guide to PMID 11164664 (2001): randomized controlled trial of Exogenous HGH, sermorelin & older GHRPs (why they're passed over) in 20 patients.

Key Facts

PMID
11164664
Journal
Burns : journal of the International Society for Burn Injuries
Year
2001
Study type
Randomized Controlled Trial
Authors
Akçay MN et al. (5 authors)
DOI
10.1016/s0305-4179(00)00056-5

What This Study Did, in Plain Language

What Was Tested

The paper reports a study of Exogenous HGH, sermorelin & older GHRPs (why they're passed over), published as a randomized controlled trial.

Creatinine excreted in urine is accepted as an indicator of catabolism of muscle mass.

Growth hormone (GH) is one of the most potent anabolic agents.

Who Took Part

The study group was 20 patients.

By PubMed's age tags, the people studied were teenagers, adults and middle-aged adults, both men and women.

How the Study Was Run

The researchers set it up as a randomized study.

The patients were allocated by chance, so the Exogenous HGH, sermorelin & older GHRPs (why they're passed over) group and the comparison group should start out alike.

What Was Measured

The researchers investigated the effect of GH on 24-h urinary creatinine levels as an indicator of catabolism of muscle mass in burned patients.

Topics PubMed links to this paper include Burns, Creatinine, Human Growth Hormone and Muscles.

What This Means in Plain Language

The paper is a randomized study of Exogenous HGH, sermorelin & older GHRPs (why they're passed over) in 20 patients.

With fewer than 40 people, it is a small study, so it is better read as an early signal for further research than as a settled answer.

The publication is from 2001 (Burns : journal of the International Society for Burn Injuries), a journal based in Netherlands.

More context: the Exogenous HGH, sermorelin & older GHRPs (why they're passed over) compound page, all human trials.

Our Notes on the Compound

Exogenous HGH, sermorelin & older GHRPs (why they're passed over): Constant levels suppress the body's own GHRH, raise somatostatin and dull pituitary response.

Related Pages

Source: PubMed record. This explanation is written by PeptideWhiz from the public record. For research and education only. Not medical advice; no dosing information is given.