Anticalculus efficacy of an antiseptic mouthrinse containing zinc chloride.

What Was Tested

Researchers studied Chlorides in this randomized controlled trial publication.

Who Took Part

The study group was 334 subjects.

By PubMed's age tags, the people studied were teenagers, adults, middle-aged adults and older adults, both men and women.

After undergoing a dental prophylaxis, 334 subjects with a moderate rate of calculus formation were stratified and randomly assigned to one of three groups: positive control (using a tartar-control toothpaste and an antiseptic rinse), negative control (using a regular toothpaste and an antiseptic mouthrinse) or experimental (using a regular dentifrice and a tartar-control mouthrinse).

How the Study Was Run

In design terms this was a randomized and double-blind study.

The subjects were allocated by chance, so the Chlorides group and the comparison group should start out alike.

Neither the subjects nor the staff measuring them knew who was on Chlorides, so expectations could not easily colour the readings.

What Was Measured

The subject headings attached to it are Analysis of Variance, Chi-Square Distribution, Chlorides, Dental Calculus, Drug Combinations, Mouthwashes and Odds Ratio.

What This Means in Plain Language

The paper is a randomized and double-blind study of Chlorides in 334 subjects.

With several hundred people or more, it is a fairly large study for this kind of research.

Its findings take up roughly 4 sentences of the abstract and are left out here on purpose; the source paper is the place to read them.

The publication is from 2001 (Journal of the American Dental Association (1939)), a journal based in England.

More context: all human trials.