Effects of growth hormone (GH) administration on homocyst(e)ine levels in men with GH deficiency: a randomized controlled trial.

What Was Tested

Researchers studied Exogenous HGH, sermorelin & older GHRPs (why they're passed over) in this randomized controlled trial publication.

The effect of GH replacement on homocyst(e)ine has not been investigated to date.

The researchers evaluated the effect of GH replacement on fasting homocyst(e)inemia in a group of men with adult-onset GH deficiency in a randomized, single blind, placebo-controlled trial.

Who Took Part

By PubMed's age tags, the people studied were adults and middle-aged adults, men only.

Nutritional assessment, body composition, total T(4), thyroid hormone binding index, and free T(4) index were assessed every 6 months.

How the Study Was Run

The researchers set it up as a randomized, single-blind and placebo-controlled study.

The participants were allocated by chance, so the Exogenous HGH, sermorelin & older GHRPs (why they're passed over) group and the comparison group should start out alike.

Only one side, usually the participants, was kept unaware of whether Exogenous HGH, sermorelin & older GHRPs (why they're passed over) was given.

The comparison arm used a placebo, so changes seen with Exogenous HGH, sermorelin & older GHRPs (why they're passed over) could be set against what happens without it.

Anthropometry, IGF-I levels, insulin, and glucose were measured at 1, 3, 6, 12, and 18 months.

What Was Measured

The researchers evaluated the effect of GH replacement on fasting homocyst(e)inemia in a group of men with adult-onset GH deficiency in a randomized, single blind, placebo-controlled trial.

Fasting serum homocyst(e)ine, folate, vitamin B12, and total T(3) levels were determined at baseline and 6 and 18 months.

The subject headings attached to it are Folic Acid, Growth Hormone, Homocysteine, Homocystine, Nutrition Assessment, Thyroid Hormones and Vitamin B 12.

What This Means in Plain Language

The paper is a randomized, single-blind and placebo-controlled study of Exogenous HGH, sermorelin & older GHRPs (why they're passed over).

The publication is from 2001 (The Journal of clinical endocrinology and metabolism), a journal based in United States.

More context: the Exogenous HGH, sermorelin & older GHRPs (why they're passed over) compound page, all human trials.