Endurance training and GH administration in elderly women: effects on abdominal adipose tissue lipolysis.

What Was Tested

This randomized controlled trial looks at Human Growth Hormone.

In the present study, the effect of endurance training alone and endurance training combined with recombinant human growth hormone (rhGH) administration on subcutaneous abdominal adipose tissue lipolysis was investigated.

Sixteen healthy women [age 75 +/- 2 yr (mean +/- SE)] underwent a 12-wk endurance training program on a cycle ergometer. rhGH was administered in a randomized, double-blinded, placebo-controlled design in addition to the training program.

Who Took Part

PubMed indexes the participants as older adults and people over 80, women only.

How the Study Was Run

The researchers set it up as a randomized, double-blind and placebo-controlled study.

The participants were allocated by chance, so the Human Growth Hormone group and the comparison group should start out alike.

Neither the participants nor the staff measuring them knew who was on Human Growth Hormone, so expectations could not easily colour the readings.

The comparison arm used a placebo, so changes seen with Human Growth Hormone could be set against what happens without it.

What Was Measured

Subcutaneous abdominal adipose tissue lipolysis was estimated by means of microdialysis combined with measurements of subcutaneous abdominal adipose tissue blood flow (ATBF; (133)Xe washout).

PubMed files the paper under topics including Abdomen, Adipose Tissue, Biomarkers, Blood Glucose, Body Composition, Calorimetry, Indirect and Epinephrine.

What This Means in Plain Language

The paper is a randomized, double-blind and placebo-controlled study of Human Growth Hormone.

The publication is from 2001 (American journal of physiology. Endocrinology and metabolism), a journal based in United States.

More context: the related Exogenous HGH, sermorelin & older GHRPs (why they're passed over) library page, all human trials.