Induction of ovulation in World Health Organization group II anovulatory women undergoing follicular stimulation with recombinant human follicle-stimulating hormone: a comparison of recombinant human chorionic gonadotropin (rhCG) and urinary hCG

What Was Tested

The paper reports a study of hCG (human chorionic gonadotropin), published as a randomized controlled trial.

Who Took Part

By PubMed's age tags, the people studied were adults, women only.

One hundred ninety-eight WHO group II anovulatory women, aged 20 to 38 years.

How the Study Was Run

In design terms this was a randomized, double-blind, multicenter and parallel-group study.

The participants were allocated by chance, so the hCG (human chorionic gonadotropin) group and the comparison group should start out alike.

Neither the participants nor the staff measuring them knew who was on hCG (human chorionic gonadotropin), so expectations could not easily colour the readings.

Running at several centres spread the hCG (human chorionic gonadotropin) study over different clinics and patient groups.

The hCG (human chorionic gonadotropin) group and the comparison group ran side by side rather than switching.

Phase III, double-blind, double-dummy, randomized, parallel-group, multicenter study.

Nineteen academic and private tertiary care infertility centers in Europe, Israel, Canada, and Australia.

Blood samples were collected and ultrasound examinations performed during stimulation and after hCG administration.

What Was Measured

Topics PubMed links to this paper include Anovulation, Chorionic Gonadotropin, Follicle Stimulating Hormone, Ovarian Follicle, Ovulation, Ovulation Induction and Pregnancy Outcome.

What This Means in Plain Language

The paper is a randomized, double-blind and multicenter study of hCG (human chorionic gonadotropin).

Its findings take up roughly 5 sentences of the abstract and are left out here on purpose; the source paper is the place to read them.

The publication is from 2001 (Fertility and sterility), a journal based in United States.

More context: the hCG (human chorionic gonadotropin) compound page, all human trials.