Changes in quality of life after hormonal treatment of endometriosis

What Was Tested

The paper reports a study of Nafarelin in the context of endometriosis, published as a randomized controlled trial.

Who Took Part

The abstract describes 48 women taking part.

PubMed indexes the participants as teenagers, adults and middle-aged adults, women only.

In a prospective, randomized, double-blind, double-dummy study on 48 women with verified endometriosis, the pain pattern and quality of life were registered before, during and after treatment with nafarelin or medroxyprogesterone acetate.

How the Study Was Run

In design terms this was a randomized and double-blind study.

The women were allocated by chance, so the Nafarelin group and the comparison group should start out alike.

Blinding on both sides kept the women and researchers unaware of who received Nafarelin.

ANOVA analysis was used for normally distributed variables and Friedman's analysis and Mann-Whitney U-test for non normally distributed variables.

What Was Measured

The subject headings attached to it are Anxiety, Depression, Endometriosis, Medroxyprogesterone Acetate, Nafarelin, Patient Dropouts and Pelvic Pain.

What This Means in Plain Language

The paper is a randomized and double-blind study of Nafarelin in 48 women in people with endometriosis.

The abstract goes on to report its results in about 8 sentences; this page does not restate them, so read the paper for the findings and their limits.

The publication is from 2001 (Acta obstetricia et gynecologica Scandinavica), a journal based in United States.

More context: the Nafarelin compound page, Endometriosis research.