Gonadotrophin releasing hormone agonist treatment with or without recombinant human GH in adopted children with early puberty.

What Was Tested

This randomized controlled trial looks at Human Growth Hormone.

Early onset of puberty is frequently observed in adopted children.

Who Took Part

The study group was 30 children.

By PubMed's age tags, the people studied were children, both men and women.

Mean age (SD) at start of treatment was 9.6 (0.9) years in girls and predicted adult height (PAH) using a segmented bone age (BA) assessment method was 148.0 (5.3) cm.

How the Study Was Run

The researchers set it up as a randomized study.

Because people in this Human Growth Hormone study were split into groups at random, differences between the groups are less likely to reflect who happened to join each one.

What Was Measured

PubMed files the paper under topics including Adoption, Anthropometry, Body Height, Emigration and Immigration, Growth, Human Growth Hormone and Luteolytic Agents.

What This Means in Plain Language

The paper is a randomized study of Human Growth Hormone in 30 children.

With fewer than 40 people, it is a small study, so it is better read as an early signal for further research than as a settled answer.

Its findings take up roughly 6 sentences of the abstract and are left out here on purpose; the source paper is the place to read them.

The publication is from 2001 (Clinical endocrinology), a journal based in England.

More context: the related Exogenous HGH, sermorelin & older GHRPs (why they're passed over) library page, all human trials.