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Effects of monounsaturated enriched sunflower oil on CHD risk factors including LDL size and copper-induced LDL oxidation
Plain-language guide to PMID 11506059 (2001): crossover randomized controlled trial study of Copper (Supplement) in 14 women.
Key Facts
- PMID
- 11506059
- Journal
- Journal of the American College of Nutrition
- Year
- 2001
- Study type
- Randomized Controlled Trial
- Authors
- Ashton EL et al. (3 authors)
- DOI
- 10.1080/07315724.2001.10719052
What This Study Did, in Plain Language
What Was Tested
This randomized controlled trial paper looks at Copper (Supplement).
To compare the effects of a diet high in monounsaturated enriched sunflower oil and a low fat diet on CHD risk factors including in vitro Cu-induced LDL oxidation and LDL size, lipids, lipoproteins, glucose and insulin.
Who Took Part
According to the abstract, 14 women were involved.
By PubMed's age tags, the people studied were adults and middle-aged adults, both men and women.
Fourteen healthy males 35 to 55 years of age and 14 healthy postmenopausal women 50 to 60 years of age completed the dietary intervention.
Two subjects did not complete the study, and their data were not included.
How the Study Was Run
The design is described as randomized and crossover.
Because people in this Copper (Supplement) study were split into groups at random, differences between the groups are less likely to reflect who happened to join each one.
In the crossover set-up each of the women took both Copper (Supplement) and the comparison in turn, acting as their own control.
A randomized crossover dietary intervention.
Each dietary period was one month.
What Was Measured
The subject headings attached to it are Blood Glucose, Cholesterol, Cholesterol, HDL, Cholesterol, LDL, Copper, Coronary Disease and Diet, Fat-Restricted.
What This Means in Plain Language
The paper is a randomized and crossover study of Copper (Supplement) in 14 women.
With fewer than 40 people, it is a small study, so it is better read as an early signal for further research than as a settled answer.
Its findings take up roughly 5 sentences of the abstract and are left out here on purpose; the source paper is the place to read them.
The publication is from 2001 (Journal of the American College of Nutrition), a journal based in United States.
More context: the Copper (Supplement) compound page, all human trials.
Our Notes on the Compound
Copper (Supplement): The active site of cytochrome c oxidase is described as containing copper ions that are essential for electron transfer.
Related Pages
Source: PubMed record. This explanation is written by PeptideWhiz from the public record. For research and education only. Not medical advice; no dosing information is given.