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Prospective randomized trial using laser acupuncture versus desmopressin in the treatment of nocturnal enuresis

Plain-language guide to PMID 11528199 (2001): randomized controlled trial study of Vasopressin and Desmopressin.

Key Facts

PMID
11528199
Journal
European urology
Year
2001
Study type
Randomized Controlled Trial
Authors
Radmayr C et al. (4 authors)
DOI
10.1159/000049773

What This Study Did, in Plain Language

What Was Tested

This randomized controlled trial paper looks at Vasopressin and Desmopressin.

Several treatment modalities for children suffering from monosymptomatic nocturnal enuresis are available, but desmopressin is a well-established option.

On the other hand, alternative nonpharmacological therapies such as laser acupuncture are more frequently requested by the parents.

All children were investigated after a minimum follow-up period of 6 month to evaluate the duration of the response.

Who Took Part

By PubMed's age tags, the people studied were young children, children and teenagers, both men and women.

Forty children aged over 5 years presenting with primary nocturnal enuresis underwent a previous evaluation of their voiding function to assure normal voiding patterns and a high nighttime urine production.

Then the children were randomized into two groups: group A children were treated with desmopressin alone, and group B children underwent laser acupuncture.

How the Study Was Run

The design is described as randomized.

Because people in this Vasopressin study were split into groups at random, differences between the groups are less likely to reflect who happened to join each one.

What Was Measured

PubMed files the paper under topics including Acupuncture Therapy, Deamino Arginine Vasopressin, Enuresis, Laser Therapy and Renal Agents.

What This Means in Plain Language

The paper is a randomized study of Vasopressin and Desmopressin.

The abstract goes on to report its results in about 8 sentences; this page does not restate them, so read the paper for the findings and their limits.

The publication is from 2001 (European urology), a journal based in Switzerland.

More context: the Vasopressin compound page and the Desmopressin compound page, all human trials.

Our Notes on the Compounds

Vasopressin: A 9-amino-acid hormone (antidiuretic hormone) that controls water balance and blood vessel tone; used in septic shock.

Desmopressin: A synthetic vasopressin analog (DDAVP) used for bedwetting, diabetes insipidus and some bleeding disorders.

Related Pages

Source: PubMed record. This explanation is written by PeptideWhiz from the public record. For research and education only. Not medical advice; no dosing information is given.