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Effects of growth hormone on in vitro maturation of germinal vesicle of human oocytes retrieved from small antral follicles.

Plain-language guide to PMID 11599461 (2001): randomized controlled trial of Exogenous HGH, sermorelin & older GHRPs (why they're passed over) in 88 women.

Key Facts

PMID
11599461
Journal
Journal of assisted reproduction and genetics
Year
2001
Study type
Randomized Controlled Trial
Authors
Hassan HA et al. (4 authors)
DOI
10.1023/a:1016630603560

What This Study Did, in Plain Language

What Was Tested

This randomized controlled trial looks at Exogenous HGH, sermorelin & older GHRPs (why they're passed over).

Evaluation of the effect of GH, administered in vivo, on in vitro maturation of human GV oocytes obtained from small follicles.

Who Took Part

The study group was 88 women.

By PubMed's age tags, the people studied were adults, women only.

The study included 88 ICSI women stimulated with long agonist protocol.

They were randomly allocated to two groups (Group 1, 44 women with 86 GV oocytes), were cotreated with GH (Group 2, no GH: 44 women with 67 GV oocytes).

How the Study Was Run

In design terms this was a randomized study.

Because people in this Exogenous HGH, sermorelin & older GHRPs (why they're passed over) study were split into groups at random, differences between the groups are less likely to reflect who happened to join each one.

GV oocytes from small follicles were matured in vitro, injected, and their development observed.

What Was Measured

The subject headings attached to it are Growth Hormone, Oocytes, Ovarian Follicle, Ovulation Induction, Pregnancy Rate and Sperm Injections, Intracytoplasmic.

What This Means in Plain Language

The paper is a randomized study of Exogenous HGH, sermorelin & older GHRPs (why they're passed over) in 88 women.

Results are reported in around 5 sentences of the abstract; we leave them to the paper itself rather than summarise them.

The publication is from 2001 (Journal of assisted reproduction and genetics), a journal based in Netherlands.

More context: the Exogenous HGH, sermorelin & older GHRPs (why they're passed over) compound page, all human trials.

Our Notes on the Compound

Exogenous HGH, sermorelin & older GHRPs (why they're passed over): Constant levels suppress the body's own GHRH, raise somatostatin and dull pituitary response.

Related Pages

Source: PubMed record. This explanation is written by PeptideWhiz from the public record. For research and education only. Not medical advice; no dosing information is given.