Somatotropic regulation of fish growth and adiposity: growth hormone (GH) and somatolactin (SL) relationship.

What It Covers

This review looks at Exogenous HGH, sermorelin & older GHRPs (why they're passed over).

Changes of growth rates, and plasma IGF-I and GH levels are also found in response to changes in diet composition and ration size, which may serve to assess the suitability of feeding regimes in aquaculture practice.

Why It Was Studied

Growth hormone (GH) and insulin-like growth factors (IGFs) play a major role in fish development and metabolism, and several studies have allowed discernment of a complex and tissue-specific collection of salmonid IGF-I transcripts (Ea-4, Ea-3, Ea-2, Ea-1), which are the result of the alternative splicing of the E-domain region.

However, the pattern of IGF-I expression is different in non-salmonid fish, and only one or two transcripts (Ea-4, Ea-2) have been detected in hepatic and extrahepatic tissues of common carp, barramundi, black sea bream and gilthead sea bream.

What Was Measured

Despite this, when comparisons are made within Mediterranean fish species (European sea bass, common dentex and gilthead sea bream), plasma IGF-I levels are consistent with fish species differences in growth rates.

Regulation of plasma somatolactin (SL) levels is also examined in gilthead sea bream, and the resulting plasma SL profile differs from that of GH.

Topics PubMed links to this paper include Adipose Tissue, Alternative Splicing, Energy Metabolism, Fish Proteins, Fishes, Food Deprivation and Glycoproteins.

What This Means in Plain Language

This is a review of Exogenous HGH, sermorelin & older GHRPs (why they're passed over).

The publication is from 2001 (Comparative biochemistry and physiology. Toxicology & pharmacology : CBP), a journal based in United States.

More context: the Exogenous HGH, sermorelin & older GHRPs (why they're passed over) compound page, all human trials.