← Human Trials & Peer-Reviewed Studies
Fat-soluble vitamin status is not affected by diacylglycerol consumption.
Plain-language guide to PMID 11786648 (2001): double-blind randomized controlled trial of Vitamin A and Vitamin E in 27 men.
Key Facts
- PMID
- 11786648
- Journal
- Annals of nutrition & metabolism
- Year
- 2001
- Study type
- Randomized Controlled Trial
- Authors
- Watanabe H et al. (12 authors)
- DOI
- 10.1159/000046736
What This Study Did, in Plain Language
What Was Tested
This randomized controlled trial looks at Vitamin A and Vitamin E.
The objective of this study was to examine the effect of dietary diacylglycerol (DAG) on the bioavailability of fat-soluble vitamins in comparison with triacylglycerol (TAG).
Who Took Part
The study group was 27 men.
The age groups tagged for this paper are adults and middle-aged adults, men only.
The researchers conducted a long-term administration test of DAG and TAG in 27 healthy men aged 27-47 years.
After measuring baseline values, subjects were randomized into two groups, one group (n = 15) was given DAG and the other (n = 12) was given TAG.
How the Study Was Run
The researchers set it up as a randomized and double-blind study.
Because people in this Vitamin A study were split into groups at random, differences between the groups are less likely to reflect who happened to join each one.
As a double-blind Vitamin A study, the assignments were hidden from both participants and investigators until the end.
At 4, 8 and 12 weeks, fasting blood samples were drawn and serum levels of vitamin A, E, and D were measured.
What Was Measured
PubMed files the paper under topics including Analysis of Variance, Biological Availability, Diglycerides, Intestinal Absorption, Nutritional Status, Triglycerides and Vitamin A.
What This Means in Plain Language
The paper is a randomized and double-blind study of Vitamin A and Vitamin E in 27 men.
With fewer than 40 people, it is a small study, so it is better read as an early signal for further research than as a settled answer.
Its findings take up roughly 4 sentences of the abstract and are left out here on purpose; the source paper is the place to read them.
The publication is from 2001 (Annals of nutrition & metabolism), a journal based in Switzerland.
More context: all human trials.
Related Pages
Source: PubMed record. This explanation is written by PeptideWhiz from the public record. For research and education only. Not medical advice; no dosing information is given.