[Therapeutic effect of weikangfu on gastric precancerous disorder with spleen deficiency syndrome and its effect of gastric mucosal zinc, copper, cyclic adenosine monophosphate, superoxide dismutase, lipid peroxide and 3H-TdR lymphocyte conversion test].

What Was Tested

This randomized controlled trial looks at the intervention named in the title.

To observe the clinical therapeutic effect of Weikangfu granule (WKF) on intestinal metaplasia (IM), atypical proliferation (ATP) and its therapeutic mechanism.

Who Took Part

The study group was 54 patients.

By PubMed's age tags, the people studied were adults, middle-aged adults and older adults, both men and women.

Sixty-one patients (treated group) were diagnosed by integrated TCM and western medicine (WM), and treated according to Syndrome Differentiation, the amount of WKF was adjusted according to various Syndromes.

The control group consisted of 54 patients, took Weisu granule without considering their Syndromes.

How the Study Was Run

In design terms this was a randomized study.

Random assignment meant chance, not the researchers, decided who got the intervention named in the title and who got the comparison, which limits bias.

Besides, 15 healthy subjects comprised of the control group.

Gastroscopy was conducted both before and after the treatment, mucosal sample was taken from antral region of stomach for pathological changes, for IM classification through histochemical staining and for determination of gastric mucosal Zn, Cu, cAMP, SOD, serum LPO and 3H-TdR lymphocyte conversion test (LCT).

What Was Measured

The subject headings attached to it are Copper, Cyclic AMP, Gastric Mucosa, Lipid Peroxides, Precancerous Conditions, Stomach Neoplasms and Superoxide Dismutase.

What This Means in Plain Language

The paper is a randomized study in 54 patients.

Results are reported in around 3 sentences of the abstract; we leave them to the paper itself rather than summarise them.

The publication is from 2000 (Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine), a journal based in China.

More context: all human trials.