Magnesium-supplemented warm blood cardioplegia in patients undergoing coronary artery revascularization.

What Was Tested

The paper reports a study of Vitamin D, K2, Magnesium and Zinc, published as a randomized controlled trial.

The aim of this study was to compare the effects of intermittent warm blood cardioplegia with and without Mg2+ supplementation on the early postoperative clinical outcomes in patients undergoing both elective or urgent CABG.

Who Took Part

PubMed indexes the participants as middle-aged adults and older adults, both men and women.

Four hundred patients undergoing CABG were prospectively randomized to receive either blood cardioplegia without Mg2+ (BC, n = 200) or supplemented with Mg2+ (BC-Mg2+, n = 200).

How the Study Was Run

The design is described as randomized and double-blind.

Because people in this Vitamin D, K2, Magnesium and Zinc study were split into groups at random, differences between the groups are less likely to reflect who happened to join each one.

Neither the participants nor the staff measuring them knew who was on Vitamin D, K2, Magnesium and Zinc, so expectations could not easily colour the readings.

Serial plasma Mg2+ concentrations were recorded at base line and postoperatively from days 1 to 4.

What Was Measured

The subject headings attached to it are Atrial Fibrillation, Cardioplegic Solutions, Coronary Artery Bypass, Heart Arrest, Induced, Intraoperative Complications, Magnesium and Postoperative Complications.

What This Means in Plain Language

The paper is a randomized and double-blind study of Vitamin D, K2, Magnesium and Zinc.

The abstract goes on to report its results in about 5 sentences; this page does not restate them, so read the paper for the findings and their limits.

The publication is from 2002 (The Annals of thoracic surgery), a journal based in Netherlands.

More context: the Vitamin D, K2, Magnesium and Zinc compound page, all human trials.