← Human Trials & Peer-Reviewed Studies

Combination of recombinant human growth hormone and glutamine-enriched total parenteral nutrition to surgical patients: effects on circulating amino acids.

Plain-language guide to PMID 11883998 (2001): double-blind randomized controlled trial of Exogenous HGH, sermorelin & older GHRPs (why they're passed over).

Key Facts

PMID
11883998
Journal
Clinical nutrition (Edinburgh, Scotland)
Year
2001
Study type
Randomized Controlled Trial
Authors
Kolstad O et al. (5 authors)
DOI
10.1054/clnu.2001.0478

What This Study Did, in Plain Language

What Was Tested

This randomized controlled trial looks at Exogenous HGH, sermorelin & older GHRPs (why they're passed over).

The aim of this study was to evaluate the additive effects of rhGH and GLN on plasma amino acids postoperatively.

Who Took Part

The age groups tagged for this paper are adults and middle-aged adults, women only.

How the Study Was Run

In design terms this was a randomized, double-blind and placebo-controlled study.

Random assignment meant chance, not the researchers, decided who got Exogenous HGH, sermorelin & older GHRPs (why they're passed over) and who got the comparison, which limits bias.

Neither the participants nor the staff measuring them knew who was on Exogenous HGH, sermorelin & older GHRPs (why they're passed over), so expectations could not easily colour the readings.

A placebo (an inactive look-alike) gave the Exogenous HGH, sermorelin & older GHRPs (why they're passed over) group a baseline to be compared against.

Group III (n=10) received glutamine-enriched TPN as the second group, but rhGH was replaced by placebo.

What Was Measured

Topics PubMed links to this paper include Amino Acids, Cholecystectomy, Laparoscopic, Drug Synergism, Glutamine, Human Growth Hormone, Parenteral Nutrition, Total and Perioperative Care.

What This Means in Plain Language

The paper is a randomized, double-blind and placebo-controlled study of Exogenous HGH, sermorelin & older GHRPs (why they're passed over).

Its findings take up roughly 6 sentences of the abstract and are left out here on purpose; the source paper is the place to read them.

The publication is from 2001 (Clinical nutrition (Edinburgh, Scotland)), a journal based in England.

More context: the Exogenous HGH, sermorelin & older GHRPs (why they're passed over) compound page, all human trials.

Our Notes on the Compound

Exogenous HGH, sermorelin & older GHRPs (why they're passed over): Constant levels suppress the body's own GHRH, raise somatostatin and dull pituitary response.

Related Pages

Source: PubMed record. This explanation is written by PeptideWhiz from the public record. For research and education only. Not medical advice; no dosing information is given.