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Short boys treated with growth hormone show normal progression of testicular size and achieve normal serum testosterone concentrations.
Plain-language guide to PMID 11980624 (2002): clinical trial of Exogenous HGH, sermorelin & older GHRPs (why they're passed over) in 77 boys.
Key Facts
- PMID
- 11980624
- Journal
- European journal of endocrinology
- Year
- 2002
- Study type
- Clinical Trial
- Authors
- Ankarberg-Lindgren C et al. (3 authors)
- DOI
- 10.1530/eje.0.1460681
What This Study Did, in Plain Language
What Was Tested
This clinical trial looks at Exogenous HGH, sermorelin & older GHRPs (why they're passed over).
To determine whether there is evidence for impaired testicular function at final height in short boys treated with growth hormone (GH) during their childhood and adolescence.
Who Took Part
The study group was 77 boys.
The age groups tagged for this paper are young children, children and teenagers, men only.
One hundred and eleven boys fulfilled the criteria.
Testicular volumes were determined by orchidometer in each boy when GH treatment was started and at final height.
How the Study Was Run
The analysis was restricted to males who had isolated GH deficiency or idiopathic short stature, and who were included in the Swedish National Registry and the Swedish GH trials.
Samples for testosterone measurements were collected from 77 boys at final height, and were measured by RIA.
What Was Measured
Topics PubMed links to this paper include Body Height, Circadian Rhythm, Growth Hormone, Metabolism, Inborn Errors, Osmolar Concentration, Testis and Testosterone.
What This Means in Plain Language
This is a clinical trial of Exogenous HGH, sermorelin & older GHRPs (why they're passed over) in 77 boys.
Its findings take up roughly 2 sentences of the abstract and are left out here on purpose; the source paper is the place to read them.
The publication is from 2002 (European journal of endocrinology), a journal based in England.
More context: the Exogenous HGH, sermorelin & older GHRPs (why they're passed over) compound page, all human trials.
Our Notes on the Compound
Exogenous HGH, sermorelin & older GHRPs (why they're passed over): Constant levels suppress the body's own GHRH, raise somatostatin and dull pituitary response.
Related Pages
Source: PubMed record. This explanation is written by PeptideWhiz from the public record. For research and education only. Not medical advice; no dosing information is given.