Iron indexes and total antioxidant status in response to soy protein intake in perimenopausal women.

What Was Tested

The paper reports a study of Zinc, published as a randomized controlled trial.

The objective was to determine the effect of soy-protein isolate (SPI) intake and iron indexes on plasma total antioxidant status (TAS) in perimenopausal women after control for other contributing factors.

Why It Was Studied

Elevated iron stores, oxidative stress, and estrogen deficiency may place postmenopausal women at greater risk of heart disease and cancer than premenopausal women.

Who Took Part

PubMed indexes the participants as adults and middle-aged adults, women only.

Perimenopausal women (n = 69) were randomly assigned (double blind) to treatment: isoflavone-rich SPI (SPI+; n = 24), isoflavone-poor SPI (SPI-; n = 24), or whey protein (control; n = 21).

How the Study Was Run

The design is described as randomized and double-blind.

Because people in this Zinc study were split into groups at random, differences between the groups are less likely to reflect who happened to join each one.

As a double-blind Zinc study, the assignments were hidden from both participants and investigators until the end.

Plasma TAS, serum ferritin, serum iron, transferrin saturation, and hemoglobin were measured at baseline, week 12, and week 24.

What Was Measured

The subject headings attached to it are Antioxidants, Climacteric, Diet, Estrone, Ferritins, Fishes and Hemoglobins.

What This Means in Plain Language

The paper is a randomized and double-blind study of Zinc.

Its findings take up roughly 4 sentences of the abstract and are left out here on purpose; the source paper is the place to read them.

The publication is from 2002 (The American journal of clinical nutrition), a journal based in United States.

More context: the related Vitamin D, K2, Magnesium and Zinc library page, all human trials.