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Intravenous magnesium sulphate in the acute treatment of migraine without aura and migraine with aura. A randomized, double-blind, placebo-controlled study.
Plain-language guide to PMID 12110110 (2002): double-blind randomized controlled trial of Anti-Inflammatory Agents, Non-Steroidal, migraine.
Key Facts
- PMID
- 12110110
- Journal
- Cephalalgia : an international journal of headache
- Year
- 2002
- Study type
- Randomized Controlled Trial
- Authors
- Bigal ME et al. (4 authors)
- DOI
- 10.1046/j.1468-2982.2002.00364.x
What This Study Did, in Plain Language
What Was Tested
The paper reports a study of Anti-Inflammatory Agents, Non-Steroidal in the context of migraine, published as a randomized controlled trial.
The researchers used seven parameters of analgesic evaluation and an analogue scale to assess nausea, photophobia and phonophobia.
Why It Was Studied
This randomized, double-blind, placebo-controlled study assesses the effect of magnesium sulphate on the pain and associated symptoms in patients with migraine without aura and migraine with aura.
There was also no statistical difference in relief of nausea.
Who Took Part
The age groups tagged for this paper are adults, both men and women.
How the Study Was Run
The researchers set it up as a randomized, double-blind and placebo-controlled study.
Because people in this Anti-Inflammatory Agents, Non-Steroidal study were split into groups at random, differences between the groups are less likely to reflect who happened to join each one.
Blinding on both sides kept the participants and researchers unaware of who received Anti-Inflammatory Agents, Non-Steroidal.
A placebo (an inactive look-alike) gave the Anti-Inflammatory Agents, Non-Steroidal group a baseline to be compared against.
What Was Measured
This randomized, double-blind, placebo-controlled study assesses the effect of magnesium sulphate on the pain and associated symptoms in patients with migraine without aura and migraine with aura.
The subject headings attached to it are Acute Disease, Anti-Inflammatory Agents, Non-Steroidal, Magnesium Sulfate, Migraine with Aura, Migraine without Aura, Nausea and Pain Measurement.
What This Means in Plain Language
The paper is a randomized, double-blind and placebo-controlled study of Anti-Inflammatory Agents, Non-Steroidal in people with migraine.
The publication is from 2002 (Cephalalgia : an international journal of headache), a journal based in England.
More context: Migraine research.
Related Pages
Source: PubMed record. This explanation is written by PeptideWhiz from the public record. For research and education only. Not medical advice; no dosing information is given.