Impact of supplement with Lactobacillus- and Bifidobacterium-containing yogurt on triple therapy for Helicobacter pylori eradication.

What Was Tested

Researchers studied Amoxicillin in this randomized controlled trial publication.

To test whether supplements of Lactobacillus- and Bifidobacterium-containing yogurt (AB-Yogurt) affect the success of Helicobacter pylori eradication.

Who Took Part

According to the abstract, 22 patients were involved.

PubMed indexes the participants as adults and middle-aged adults, both men and women.

One hundred and sixty H. pylori-infected patients were randomized into a triple-plus-yogurt group or a triple-only group, receiving 1 week of triple therapy with and without supplements of AB-Yogurt, respectively.

Eight weeks later, patients were assessed for the success of H. pylori eradication.

How the Study Was Run

The design is described as randomized.

The patients were allocated by chance, so the Amoxicillin group and the comparison group should start out alike.

The stool samples of 22 randomly selected patients, 11 from each group, were provided on enrolment, at the first week and at the fifth week for evaluation of the percentage of Bifidobacterium in anaerobes.

What Was Measured

The subject headings attached to it are 2-Pyridinylmethylsulfinylbenzimidazoles, Amoxicillin, Bifidobacterium, Clarithromycin, Combined Modality Therapy, Feces and Helicobacter Infections.

What This Means in Plain Language

The paper is a randomized study of Amoxicillin in 22 patients.

With fewer than 40 people, it is a small study, so it is better read as an early signal for further research than as a settled answer.

The abstract goes on to report its results in about 4 sentences; this page does not restate them, so read the paper for the findings and their limits.

The publication is from 2002 (Alimentary pharmacology & therapeutics), a journal based in England.

More context: all human trials.