← Human Trials & Peer-Reviewed Studies
Iron and zinc status of women and men who followed cholesterol-lowering diets.
Plain-language guide to PMID 12515414 (1998): randomized controlled trial of Cholesterol, Dietary in 213 men.
Key Facts
- PMID
- 12515414
- Journal
- Journal of the American Dietetic Association
- Year
- 1998
- Study type
- Randomized Controlled Trial
- Authors
- Retzlaff BM et al. (5 authors)
- DOI
- 10.1016/S0002-8223(98)00038-8
What This Study Did, in Plain Language
What Was Tested
This randomized controlled trial looks at Cholesterol, Dietary.
Paired t tests to compare preintervention and postintervention test results.
Two-sample t tests to compare gender, menopause status, and hormone-use groups.
Analysis of variance was performed to compare plasma zinc levels among diet-adherence subgroups.
Why It Was Studied
In this large-scale, 2-year prospective study of women and men, no adverse effects on intake or plasma indicators of iron and zinc were detected as a result of subjects being taught the NCEP step 2 diet.
Who Took Part
According to the abstract, 213 men were involved.
The age groups tagged for this paper are adults, both men and women.
Subjects attended 8 weeks of diet classes and followup counseling.
How the Study Was Run
The researchers set it up as a randomized study.
The men were allocated by chance, so the Cholesterol, Dietary group and the comparison group should start out alike.
Four-day food records, zinc protoporphyrin/ heme (ZPP/H, a measure of iron stores), hematocrit, and plasma zinc values were collected at baseline, 1 year, and 2 years.
What Was Measured
Topics PubMed links to this paper include Analysis of Variance, Cholesterol, Cholesterol, Dietary, Diet Records, Diet, Fat-Restricted, Hematocrit and Heme.
What This Means in Plain Language
The paper is a randomized study of Cholesterol, Dietary in 213 men.
The abstract goes on to report its results in about 7 sentences; this page does not restate them, so read the paper for the findings and their limits.
The publication is from 1998 (Journal of the American Dietetic Association), a journal based in United States.
More context: all human trials.
Related Pages
Source: PubMed record. This explanation is written by PeptideWhiz from the public record. For research and education only. Not medical advice; no dosing information is given.