[Effect of yiqi bushen huoxue herbs in treating children asthma and on levels of nitric oxide, endothelin-1 and serum endothelial cells]

What Was Tested

Researchers studied Endothelin-1 in this randomized controlled trial publication.

To observe the therapeutic effect of Yiqi Bushen Huoxue herbs (YQBSHX, the Chinese herbs for supplementing Qi, replenishing Kidney and activating blood circulation) on children asthma in regard to its effect on the serum levels of nitric oxide (NO), endothelin-1 (ET-1) and circulating endothelial cells (CEC).

Who Took Part

By PubMed's age tags, the people studied were infants, young children and children, both men and women.

Two hundred children with asthma were divided into two groups, the YQBSHX and the control group, and their serum levels of NO, ET-1 and CEC were detected in acute and remission stage respectively.

How the Study Was Run

In design terms this was a randomized study.

Because people in this Endothelin-1 study were split into groups at random, differences between the groups are less likely to reflect who happened to join each one.

A time span of 1 year appears in the methods.

Twenty cases in each group were followed-up for 1 year to observe the frequency of asthma attack and the changes in ET-1, NO and CEC levels.

What Was Measured

Topics PubMed links to this paper include Asthma, Drugs, Chinese Herbal, Endothelin-1, Nitric Oxide and Phytotherapy.

What This Means in Plain Language

The paper is a randomized study of Endothelin-1 over 1 year.

The abstract goes on to report its results in about 4 sentences; this page does not restate them, so read the paper for the findings and their limits.

The publication is from 2001 (Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine), a journal based in China.

More context: the Endothelin-1 compound page, all human trials.