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A randomized, controlled lower leg growth study of vitamin D supplementation to healthy children during the winter season.

Plain-language guide to PMID 12637196 (2003): double-blind randomized controlled trial of Vitamin D, K2, Magnesium and Zinc.

Key Facts

PMID
12637196
Journal
Annals of human biology
Year
2003
Study type
Randomized Controlled Trial
Authors
Schou AJ et al. (3 authors)
DOI
10.1080/0301446021000057629

What This Study Did, in Plain Language

What Was Tested

Researchers studied Vitamin D, K2, Magnesium and Zinc in this randomized controlled trial publication.

To see whether supplementation of vitamin D to healthy children during winter affects seasonal growth.

Who Took Part

By PubMed's age tags, the people studied were children and teenagers, both men and women.

How the Study Was Run

The design is described as randomized, double-blind, placebo-controlled and crossover.

The participants were allocated by chance, so the Vitamin D, K2, Magnesium and Zinc group and the comparison group should start out alike.

As a double-blind Vitamin D, K2, Magnesium and Zinc study, the assignments were hidden from both participants and investigators until the end.

A placebo (an inactive look-alike) gave the Vitamin D, K2, Magnesium and Zinc group a baseline to be compared against.

In the crossover set-up each of the participants took both Vitamin D, K2, Magnesium and Zinc and the comparison in turn, acting as their own control.

Knemometry of the right lower leg was performed on the first and last day of each period.

What Was Measured

PubMed files the paper under topics including Denmark, Dietary Supplements, Fibula, Seasons, Sunlight, Tibia and Vitamin D.

What This Means in Plain Language

The paper is a randomized, double-blind and placebo-controlled study of Vitamin D, K2, Magnesium and Zinc.

The abstract goes on to report its results in about 3 sentences; this page does not restate them, so read the paper for the findings and their limits.

The publication is from 2003 (Annals of human biology), a journal based in England.

More context: the Vitamin D, K2, Magnesium and Zinc compound page, all human trials.

Our Notes on the Compound

Vitamin D, K2, Magnesium and Zinc: Magnesium is described as required for AMPK to function.

Related Pages

Source: PubMed record. This explanation is written by PeptideWhiz from the public record. For research and education only. Not medical advice; no dosing information is given.