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Effects of alternative maternal micronutrient supplements on low birth weight in rural Nepal: double blind randomised community trial.
Plain-language guide to PMID 12637400 (2003): double-blind randomized controlled trial of Zinc and Folic Acid in 4926 women.
Key Facts
- PMID
- 12637400
- Journal
- BMJ (Clinical research ed.)
- Year
- 2003
- Study type
- Randomized Controlled Trial
- Authors
- Christian P et al. (9 authors)
- DOI
- 10.1136/bmj.326.7389.571
What This Study Did, in Plain Language
What Was Tested
Researchers studied Zinc and Folic Acid in this randomized controlled trial publication.
To assess the impact on birth size and risk of low birth weight of alternative combinations of micronutrients given to pregnant women.
Who Took Part
The abstract describes 4926 women taking part.
PubMed tags the participants as women only.
4926 pregnant women and 4130 live born infants.
How the Study Was Run
In design terms this was a randomized and double-blind study.
Because people in this Zinc study were split into groups at random, differences between the groups are less likely to reflect who happened to join each one.
As a double-blind Zinc study, the assignments were hidden from both participants and investigators until the end.
Double blind cluster randomised controlled trial.
Rural community in south eastern Nepal.
What Was Measured
Topics PubMed links to this paper include Birth Weight, Dietary Supplements, Folic Acid, Infant, Low Birth Weight, Iron, Micronutrients and Nepal.
What This Means in Plain Language
The paper is a randomized and double-blind study of Zinc and Folic Acid in 4926 women.
With several hundred people or more, it is a fairly large study for this kind of research.
Its findings take up roughly 10 sentences of the abstract and are left out here on purpose; the source paper is the place to read them.
The publication is from 2003 (BMJ (Clinical research ed.)), a journal based in England.
More context: the related Vitamin D, K2, Magnesium and Zinc library page, all human trials.
Related Library Page
Vitamin D, K2, Magnesium and Zinc: Magnesium is described as required for AMPK to function.
Related Pages
Source: PubMed record. This explanation is written by PeptideWhiz from the public record. For research and education only. Not medical advice; no dosing information is given.