Efficacy of Humalog injections before an afternoon meal and their acceptance by children and adolescents with type 1 diabetes

What Was Tested

Researchers studied Insulin Lispro in this randomized controlled trial publication.

Who Took Part

According to the abstract, 43 patients were involved.

The age groups tagged for this paper are children, both men and women.

The subjects, 43 patients with Type 1 diabetes, 16 boys and 27 girls, aged 12.4 +/- 2.4 years, were randomly assigned to the treatment (n = 20) or the untreated control group (n = 23).

The treatment was an injection of insulin lispro immediately before the afternoon meal.

How the Study Was Run

The design is described as randomized.

Because people in this Insulin Lispro study were split into groups at random, differences between the groups are less likely to reflect who happened to join each one.

The methods mention a period of 2 months.

The control group had no injection.

The treatment and the control group consumed identical types of meals for 2 months.

The mean before-dinner blood glucose was measured during the last 2 weeks of the study.

What Was Measured

PubMed files the paper under topics including Blood Glucose, Cohort Studies, Diabetes Mellitus, Type 1, Eating, Hyperglycemia, Hypoglycemic Agents and Injections.

What This Means in Plain Language

The paper is a randomized study of Insulin Lispro in 43 patients over 2 months.

The abstract goes on to report its results in about 9 sentences; this page does not restate them, so read the paper for the findings and their limits.

The publication is from 2002 (Diabetic medicine : a journal of the British Diabetic Association), a journal based in England.

More context: the Insulin Lispro compound page, all human trials.