Response of serum inhibin B and pro-alphaC levels to gonadotrophic stimulation in normal men before and after steroidal contraceptive treatment.

What Was Tested

The paper reports a study of Chorionic Gonadotropin, published as a randomized controlled trial.

Testicular regulation of inhibin B may be influenced by the germ cell complement.

Who Took Part

The abstract describes 25 men taking part.

PubMed indexes the participants as adults, men only.

The researchers examined the effects of gonadotrophin stimulation on serum inhibin B and pro-alphaC in 25 normal men at (i) control (stimulation test 1), (ii) after spermatogenic suppression induced by testosterone plus progestin treatment (stimulation test 2), and (iii) during spermatogenic recovery induced by FSH and/or hCG treatment (stimulation test 3).

How the Study Was Run

The design is described as randomized.

The men were allocated by chance, so the Chorionic Gonadotropin group and the comparison group should start out alike.

What Was Measured

Testicular regulation of inhibin B may be influenced by the germ cell complement.

PubMed files the paper under topics including Biomarkers, Chorionic Gonadotropin, Contraceptive Agents, Male, Follicle Stimulating Hormone, Gonadotropins, Inhibins and Protein Precursors.

What This Means in Plain Language

The paper is a randomized study of Chorionic Gonadotropin in 25 men.

With fewer than 40 people, it is a small study, so it is better read as an early signal for further research than as a settled answer.

Its findings take up roughly 5 sentences of the abstract and are left out here on purpose; the source paper is the place to read them.

The publication is from 2003 (Human reproduction (Oxford, England)), a journal based in England.

More context: the related hCG (human chorionic gonadotropin) library page, all human trials.