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Progression of retinopathy during pregnancy in type 1 diabetic women treated with insulin lispro

Plain-language guide to PMID 12663596 (2003): controlled clinical trial study of Insulin Lispro in 69 women, diabetic retinopathy and glaucoma.

Key Facts

PMID
12663596
Journal
Diabetes care
Year
2003
Study type
Controlled Clinical Trial
Authors
Loukovaara S et al. (4 authors)
DOI
10.2337/diacare.26.4.1193

What This Study Did, in Plain Language

What Was Tested

This controlled clinical trial paper looks at Insulin Lispro in the context of diabetic retinopathy and glaucoma.

To evaluate the progression of retinopathy during pregnancy and postpartum in (insulin-dependent) women with type 1 diabetes treated with insulin lispro or with regular human insulin.

Who Took Part

The abstract describes 69 women taking part.

By PubMed's age tags, the people studied were adults, women only.

A prospective open study of 69 pregnant women with diabetes was performed.

A total of 36 of the women were treated with insulin lispro (lispro group) and 33 were treated with conventional short-acting human insulin (regular insulin group).

How the Study Was Run

The retinopathy level was estimated by color fundus photography every trimester and postpartum.

What Was Measured

PubMed files the paper under topics including Age of Onset, Blood Pressure, Diabetes Mellitus, Type 1, Diabetic Retinopathy, Disease Progression, Hypoglycemic Agents and Insulin.

What This Means in Plain Language

This is a controlled clinical trial of Insulin Lispro in 69 women in people with diabetic retinopathy and glaucoma.

Results are reported in around 5 sentences of the abstract; we leave them to the paper itself rather than summarise them.

The publication is from 2003 (Diabetes care), a journal based in United States.

More context: the Insulin Lispro compound page, Diabetic retinopathy and glaucoma research.

Our Notes on the Compound

Insulin Lispro: A rapid-acting mealtime insulin analog; brands include Humalog, Admelog and Lyumjev.

Related Pages

Source: PubMed record. This explanation is written by PeptideWhiz from the public record. For research and education only. Not medical advice; no dosing information is given.