← Human Trials & Peer-Reviewed Studies
Physician treatment of osteoporosis in response to heel ultrasound bone mineral density reports
Plain-language guide to PMID 12665638 (2002): randomized controlled trial study of Calcitonin in 88 people, osteoporosis and bone density.
Key Facts
- PMID
- 12665638
- Journal
- Journal of clinical densitometry : the official journal of the International Society for Clinical Densitometry
- Year
- 2002
- Study type
- Randomized Controlled Trial
- Authors
- Boyd JL et al. (3 authors)
- DOI
- 10.1385/jcd:5:4:375
What This Study Did, in Plain Language
What Was Tested
The paper reports a study of Calcitonin in the context of osteoporosis and bone density, published as a randomized controlled trial.
Optimal information that should be included in ultrasound (US) heel bone mineral density (BMD) reports is not known.
The researchers screened people at health fairs using the Sahara heel US machine.
Who Took Part
The abstract describes 88 people taking part.
How the Study Was Run
In design terms this was a randomized study.
Random assignment meant chance, not the researchers, decided who got Calcitonin and who got the comparison, which limits bias.
What Was Measured
For those with a T-score of </= 1.0, letters were sent to their primary care physician notifying them of the result.
Physicians were randomly assigned to (1) a standard letter, which recommended central bone density screening (dual X-ray absorptiometry [DXA]) and treatment if the BMD was low; or (2) an extended letter, which also outlined treatment strategies based on recommended subsequent central DXA scan results for a T-score of < 1.50 and also if < 2.00.
Topics PubMed links to this paper include Bone Density, Calcaneus, Calcitonin, Calcium, Diphosphonates, Mass Screening and Osteoporosis.
What This Means in Plain Language
The paper is a randomized study of Calcitonin in 88 people in people with osteoporosis and bone density.
The publication is from 2002 (Journal of clinical densitometry : the official journal of the International Society for Clinical Densitometry), a journal based in United States.
More context: the Calcitonin compound page, Osteoporosis and bone density research.
Our Notes on the Compound
Calcitonin: A 32-amino-acid hormone that lowers blood calcium; salmon calcitonin (Miacalcin) has been used for Paget disease and osteoporosis.
Related Pages
Source: PubMed record. This explanation is written by PeptideWhiz from the public record. For research and education only. Not medical advice; no dosing information is given.