Factors that affect the variability in heart rate during endoscopic retrograde cholangiopancreatography.

What Was Tested

The paper reports a study of Glucagon, published as a randomized controlled trial.

To find out if drugs, position, and endoscopic manipulation during endoscopic retrograde cholangiopancreatography (ERCP) influence the changes in the variability of heart rate.

Who Took Part

According to the abstract, 10 volunteers were involved.

The age groups tagged for this paper are adults, middle-aged adults, older adults and people over 80, both men and women.

10 volunteers given butyscopolamine, glucagon, or saline intravenously on three different study days, and 10 patients who had ERCP without butylscopolamine or glucagon.

How the Study Was Run

The researchers set it up as a randomized and single-blind study.

Because people in this Glucagon study were split into groups at random, differences between the groups are less likely to reflect who happened to join each one.

In this single-blind Glucagon study one party knew the assignments and the other did not.

What Was Measured

PubMed files the paper under topics including Autonomic Nervous System, Butylscopolammonium Bromide, Cholangiopancreatography, Endoscopic Retrograde, Electrocardiography, Ambulatory, Gastrointestinal Agents, Glucagon and Heart Rate.

What This Means in Plain Language

The paper is a randomized and single-blind study of Glucagon in 10 volunteers.

With fewer than 40 people, it is a small study, so it is better read as an early signal for further research than as a settled answer.

Its findings take up roughly 7 sentences of the abstract and are left out here on purpose; the source paper is the place to read them.

The publication is from 2002 (The European journal of surgery = Acta chirurgica), a journal based in England.

More context: the related Glucagon library page, all human trials.