CT and MR imaging findings and their implications in the follow-up of patients with intracranial aneurysms treated with endosaccular occlusion with onyx.

What Was Tested

This clinical trial looks at Polyvinyls.

Their purpose was to describe the CT and MR features of intracranial aneurysms occluded with the liquid polymer Onyx.

Who Took Part

The abstract describes 35 patients taking part.

PubMed indexes the participants as children, teenagers, adults, middle-aged adults, older adults and people over 80, both men and women.

At two centers, 35 aneurysms in 33 patients and 11 in nine patients were treated with the polymer.

In 17 patients, adjunctive stents were placed at the aneurysm neck.

How the Study Was Run

All but three aneurysms originated from the internal carotid artery (ICA).

Eighteen were giant; 15, large; and 13, small.

Patients underwent pre- and postprocedural CT and/or MR imaging; MR angiograms (MRAs) were available in 22.

In 35 patients (38 aneurysms), 3-month and/or 1-year follow-up angiograms were obtained for correlation with sectional images.

What Was Measured

PubMed files the paper under topics including Artifacts, Carotid Artery Diseases, Carotid Artery, Internal, Cavernous Sinus, Cerebellum, Cerebral Angiography and Dimethyl Sulfoxide.

What This Means in Plain Language

This is a clinical trial of Polyvinyls in 35 patients.

With fewer than 40 people, it is a small study, so it is better read as an early signal for further research than as a settled answer.

Results are reported in around 10 sentences of the abstract; we leave them to the paper itself rather than summarise them.

The publication is from 2003 (AJNR. American journal of neuroradiology), a journal based in United States.

More context: all human trials.