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[Early use of menotropin in the treatment of varicocele]
Plain-language guide to PMID 12741348 (2003): randomized controlled trial of HMG (Human Menopausal Gonadotropin) in 60 patients.
Key Facts
- PMID
- 12741348
- Journal
- Archivio italiano di urologia, andrologia : organo ufficiale [di] Societa italiana di ecografia urologica e nefrologica
- Year
- 2003
- Study type
- Randomized Controlled Trial
- Authors
- De Rose AF et al. (5 authors)
What This Study Did, in Plain Language
What Was Tested
Researchers studied HMG (Human Menopausal Gonadotropin) in this randomized controlled trial publication.
Varicocele is the most common disease in infertile men and varicocelectomy remains the main treatment.
During the last years a lot of drugs have been proposed in association with surgery.
The aim of this study is verify the effects of the association between menotropin and subinguinal varicocelectomy on sperm parameters and pregnancy rate.
Who Took Part
The study group was 60 patients.
By PubMed's age tags, the people studied were adults, both men and women.
The researchers have tested sperm parameters before and after three, six and twelve months from surgical treatment.
How the Study Was Run
The researchers set it up as a randomized study.
Because people in this HMG (Human Menopausal Gonadotropin) study were split into groups at random, differences between the groups are less likely to reflect who happened to join each one.
After six and twelve months from varicocelectomy the researchers have verified the pregnancy rates in the three groups.
What Was Measured
The subject headings attached to it are Combined Modality Therapy, Follicle Stimulating Hormone, Gonadotropin-Releasing Hormone, Infertility, Male, Ligation, Luteinizing Hormone and Menotropins.
What This Means in Plain Language
The paper is a randomized study of HMG (Human Menopausal Gonadotropin) in 60 patients.
Results are reported in around 8 sentences of the abstract; we leave them to the paper itself rather than summarise them.
The publication is from 2003 (Archivio italiano di urologia, andrologia : organo ufficiale [di] Societa italiana di ecografia urologica e nefrologica), a journal based in Italy.
More context: the HMG (Human Menopausal Gonadotropin) compound page, all human trials.
Our Notes on the Compound
HMG (Human Menopausal Gonadotropin): Menotropins: a glycoprotein preparation that supplies follicle-stimulating hormone (FSH) and luteinizing hormone (LH) activity.
Related Pages
Source: PubMed record. This explanation is written by PeptideWhiz from the public record. For research and education only. Not medical advice; no dosing information is given.