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Recombinant human growth hormone increases thyroid hormone-binding sites in recovering severely burned children.

Plain-language guide to PMID 12744480 (2003): randomized controlled trial of Exogenous HGH, sermorelin & older GHRPs (why they're passed over) in 11 children.

Key Facts

PMID
12744480
Journal
Shock (Augusta, Ga.)
Year
2003
Study type
Randomized Controlled Trial
Authors
Connolly CM et al. (5 authors)
DOI
10.1097/01.shk.0000051758.08171.bc

What This Study Did, in Plain Language

What Was Tested

The paper reports a study of Exogenous HGH, sermorelin & older GHRPs (why they're passed over), published as a randomized controlled trial.

T4 and T3 are carried on serum transport proteins via thyroid hormone-binding sites (THBS).

This study investigated the effect of rhGH on THBS sites in burned children.

Who Took Part

According to the abstract, 11 children were involved.

The age groups tagged for this paper are children.

How the Study Was Run

The design is described as randomized and placebo-controlled.

Because people in this Exogenous HGH, sermorelin & older GHRPs (why they're passed over) study were split into groups at random, differences between the groups are less likely to reflect who happened to join each one.

A placebo (an inactive look-alike) gave the Exogenous HGH, sermorelin & older GHRPs (why they're passed over) group a baseline to be compared against.

What Was Measured

PubMed files the paper under topics including Blood Glucose, Burns, Human Growth Hormone, Insulin-Like Growth Factor Binding Protein 3, Prealbumin, Serum Albumin and Thyroxine.

What This Means in Plain Language

The paper is a randomized and placebo-controlled study of Exogenous HGH, sermorelin & older GHRPs (why they're passed over) in 11 children.

With fewer than 40 people, it is a small study, so it is better read as an early signal for further research than as a settled answer.

The publication is from 2003 (Shock (Augusta, Ga.)), a journal based in United States.

More context: the Exogenous HGH, sermorelin & older GHRPs (why they're passed over) compound page, all human trials.

Our Notes on the Compound

Exogenous HGH, sermorelin & older GHRPs (why they're passed over): Constant levels suppress the body's own GHRH, raise somatostatin and dull pituitary response.

Related Pages

Source: PubMed record. This explanation is written by PeptideWhiz from the public record. For research and education only. Not medical advice; no dosing information is given.