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The effects of magnesium prime solution on magnesium levels and potassium loss in open heart surgery.

Plain-language guide to PMID 12760983 (2003): randomized controlled trial of Magnesium.

Key Facts

PMID
12760983
Journal
Anesthesia and analgesia
Year
2003
Study type
Randomized Controlled Trial
Authors
Jian W et al. (3 authors)
DOI
10.1213/01.ANE.0000065444.21593.23

What This Study Did, in Plain Language

What Was Tested

This randomized controlled trial looks at Magnesium.

In this study, the researchers examined the effects of magnesium supplementation in the cardiopulmonary bypass (CPB) prime solution on pediatric patients' magnesium levels and potassium loss with open heart surgery.

In the magnesium group, IMg concentration was larger during CPB but not after CPB.

Who Took Part

The age groups tagged for this paper are young children, both men and women.

How the Study Was Run

The design is described as randomized and placebo-controlled.

Because people in this Magnesium study were split into groups at random, differences between the groups are less likely to reflect who happened to join each one.

The comparison arm used a placebo, so changes seen with Magnesium could be set against what happens without it.

Ionized magnesium (IMg) and urinary magnesium and potassium were measured at defined time points during and after CPB.

What Was Measured

In this study, the researchers examined the effects of magnesium supplementation in the cardiopulmonary bypass (CPB) prime solution on pediatric patients' magnesium levels and potassium loss with open heart surgery.

The subject headings attached to it are Cardiac Surgical Procedures, Cardiopulmonary Bypass, Magnesium and Potassium.

What This Means in Plain Language

The paper is a randomized and placebo-controlled study of Magnesium.

Results are reported in around 1 sentences of the abstract; we leave them to the paper itself rather than summarise them.

The publication is from 2003 (Anesthesia and analgesia), a journal based in United States.

More context: the related Vitamin D, K2, Magnesium and Zinc library page, all human trials.

Related Library Page

Vitamin D, K2, Magnesium and Zinc: Magnesium is described as required for AMPK to function.

Related Pages

Source: PubMed record. This explanation is written by PeptideWhiz from the public record. For research and education only. Not medical advice; no dosing information is given.